The Many (Inter)faces of Anti-CRISPRs: Modulation of CRISPR-Cas Structure and Dynamics by Mechanistically Diverse Inhibitors

The discovery of protein inhibitors of CRISPR-Cas systems, called anti-CRISPRs (Acrs), has enabled the development of highly controllable and precise CRISPR-Cas tools. Anti-CRISPRs share very little structural or sequential resemblance to each other or to other proteins, which raises intriguing ques...

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Detalles Bibliográficos
Autores principales: Belato, Helen B., Lisi, George P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953297/
https://www.ncbi.nlm.nih.gov/pubmed/36830633
http://dx.doi.org/10.3390/biom13020264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953297/
https://www.ncbi.nlm.nih.gov/pubmed/36830633
http://dx.doi.org/10.3390/biom13020264

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