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TMBIM4 Deficiency Facilitates NLRP3 Inflammasome Activation-Induced Pyroptosis of Trophoblasts: A Potential Pathogenesis of Preeclampsia

SIMPLE SUMMARY: Impaired invasion of extravillous trophoblasts (EVTs) results in inadequate remodelling of arteries and poor placentation, leading to preeclampsia (PE). Transmembrane BAX Inhibitor-1 Motif-containing 4 (TMBIM4) was found to promote the migration and invasion of human osteosarcoma U2-...

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Detalles Bibliográficos
Autores principales: Chen, Yuanyao, Xiao, Lin, Sun, Guoqiang, Li, Min, Yang, Hailan, Ming, Zhangyin, Zhao, Kai, Shang, Xuejun, Zhang, Huiping, Liu, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953300/
https://www.ncbi.nlm.nih.gov/pubmed/36829486
http://dx.doi.org/10.3390/biology12020208