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“Dynamical Docking” of Cyclic Dinuclear Au(I) Bis-N-heterocyclic Complexes Facilitates Their Binding to G-Quadruplexes

[Image: see text] With the aim to improve the design of metal complexes as stabilizers of noncanonical DNA secondary structures, namely, G-quadruplexes (G4s), a series of cyclic dinuclear Au(I) N-heterocyclic carbene complexes based on xanthine and benzimidazole ligands has been synthesized and char...

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Detalles Bibliográficos
Autores principales: Kaußler, Clemens, Wragg, Darren, Schmidt, Claudia, Moreno-Alcántar, Guillermo, Jandl, Christian, Stephan, Johannes, Fischer, Roland A., Leoni, Stefano, Casini, Angela, Bonsignore, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953335/
https://www.ncbi.nlm.nih.gov/pubmed/36484812
http://dx.doi.org/10.1021/acs.inorgchem.2c03041