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Co-Translational Quality Control Induced by Translational Arrest

Genetic mutations, mRNA processing errors, and lack of availability of charged tRNAs sometimes slow down or completely stall translating ribosomes. Since an incomplete nascent chain derived from stalled ribosomes may function anomalously, such as by forming toxic aggregates, surveillance systems mon...

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Detalles Bibliográficos
Autores principales: Matsuo, Yoshitaka, Inada, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953336/
https://www.ncbi.nlm.nih.gov/pubmed/36830686
http://dx.doi.org/10.3390/biom13020317