Reversibility and Low Commitment to Forward Catalysis in the Conjugation of Lipid Alkenals by Glutathione Transferase A4-4

High concentrations of electrophilic lipid alkenals formed during oxidative stress are implicated in cytotoxicity and disease. However, low concentrations of alkenals are required to induce antioxidative stress responses. An established clearance pathway for lipid alkenals includes conjugation to gl...

Descripción completa

Detalles Bibliográficos
Autores principales: Scian, Michele, Paço, Lorela, Murphree, Taylor A., Shireman, Laura M., Atkins, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953347/
https://www.ncbi.nlm.nih.gov/pubmed/36830698
http://dx.doi.org/10.3390/biom13020329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953347/
https://www.ncbi.nlm.nih.gov/pubmed/36830698
http://dx.doi.org/10.3390/biom13020329

Ejemplares similares