Identification of Inhibitors of Tubulin Polymerization Using a CRISPR-Edited Cell Line with Endogenous Fluorescent Tagging of β-Tubulin and Histone H1

Tubulin is a protein that plays a critical role in maintaining cellular structure and facilitating cell division. Inhibiting tubulin polymerization has been shown to be an effective strategy for inhibiting the proliferation of cancer cells. In the past, identifying compounds that could inhibit tubul...

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Detalles Bibliográficos
Autores principales: Khachatryan, Harutyun, Olszowy, Bartlomiej, Barrero, Carlos A., Gordon, John, Perez-Leal, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953358/
https://www.ncbi.nlm.nih.gov/pubmed/36830618
http://dx.doi.org/10.3390/biom13020249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953358/
https://www.ncbi.nlm.nih.gov/pubmed/36830618
http://dx.doi.org/10.3390/biom13020249

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