Cargando…

Functional Loss of Terminal Complement Complex Protects Rabbits from Injury-Induced Osteoarthritis on Structural and Cellular Level

The terminal complement complex (TCC) has been described as a potential driver in the pathogenesis of posttraumatic osteoarthritis (PTOA). However, sublytic TCC deposition might also play a crucial role in bone development and regeneration. Therefore, we elucidated the effects of TCC on joint-relate...

Descripción completa

Detalles Bibliográficos
Autores principales: Riegger, Jana, Joos, Helga, Möhler, Valentin, Leucht, Frank, Rading, Katrin, Kubisch, Christian, Ignatius, Anita, Huber-Lang, Markus, Brenner, Rolf E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953363/
https://www.ncbi.nlm.nih.gov/pubmed/36830586
http://dx.doi.org/10.3390/biom13020216