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Chronic Exposure to Nitric Oxide Induces P53 Mutations and Malignant-like Features in Human Breast Epithelial Cells

The small endogenous signaling molecule nitric oxide (NO) has been linked with chronic inflammation and cancer. The effects of NO are both concentration and temporally dependent; under some conditions, NO protects against damage caused by reactive oxygen species and activates P53 signaling. During c...

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Detalles Bibliográficos
Autores principales: Cheng, Robert Y. S., Burkett, Sandra, Ambs, Stefan, Moody, Terry, Wink, David A., Ridnour, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953427/
https://www.ncbi.nlm.nih.gov/pubmed/36830680
http://dx.doi.org/10.3390/biom13020311