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Oncostatin M Receptor Type II Knockout Mitigates Inflammation and Improves Survival from Sepsis in Mice

Sepsis remains one of the leading causes of death worldwide. Oncostatin M (OSM), an interleukin (IL)-6 family cytokine, can be found at high levels in septic patients. However, little is known about its role in sepsis. This study aimed to determine if the genetic knockout of OSM receptor (OSMR) type...

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Detalles Bibliográficos
Autores principales: Salim, Saad Y., AlMalki, Nour, Macala, Kimberly F., Wiedemeyer, Alyssa, Mueller, Thomas F., Churchill, Thomas A., Bourque, Stephane L., Khadaroo, Rachel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953488/
https://www.ncbi.nlm.nih.gov/pubmed/36831019
http://dx.doi.org/10.3390/biomedicines11020483