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Oncostatin M Receptor Type II Knockout Mitigates Inflammation and Improves Survival from Sepsis in Mice
Sepsis remains one of the leading causes of death worldwide. Oncostatin M (OSM), an interleukin (IL)-6 family cytokine, can be found at high levels in septic patients. However, little is known about its role in sepsis. This study aimed to determine if the genetic knockout of OSM receptor (OSMR) type...
Autores principales: | Salim, Saad Y., AlMalki, Nour, Macala, Kimberly F., Wiedemeyer, Alyssa, Mueller, Thomas F., Churchill, Thomas A., Bourque, Stephane L., Khadaroo, Rachel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953488/ https://www.ncbi.nlm.nih.gov/pubmed/36831019 http://dx.doi.org/10.3390/biomedicines11020483 |
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