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DNA Gyrase as a Target for Quinolones

Bacterial DNA gyrase is a type II topoisomerase that can introduce negative supercoils to DNA substrates and is a clinically-relevant target for the development of new antibacterials. DNA gyrase is one of the primary targets of quinolones, broad-spectrum antibacterial agents and are used as a first-...

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Detalles Bibliográficos
Autores principales: Spencer, Angela C., Panda, Siva S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953508/
https://www.ncbi.nlm.nih.gov/pubmed/36830908
http://dx.doi.org/10.3390/biomedicines11020371