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Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Phosphate Accelerates Cellular Cholesterol Efflux in THP-1 Cells

Cholesterol efflux is a major atheroprotective function of high-density lipoproteins (HDLs) which removes cholesterol from the foam cells of lipid-rich plaques in Type 2 diabetes. The dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin phosphate increases plasma glucagon-like peptide-1 (GLP-1) conc...

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Detalles Bibliográficos
Autores principales: Komatsu, Tomohiro, Abe, Satomi, Nakashima, Shihoko, Sasaki, Kei, Higaki, Yasuki, Saku, Keijiro, Miura, Shin-ichiro, Uehara, Yoshinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953524/
https://www.ncbi.nlm.nih.gov/pubmed/36830597
http://dx.doi.org/10.3390/biom13020228