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Structural Basis of the Interaction of the G Proteins, Gαi(1), Gβ(1)γ(2) and Gαi(1)β(1)γ(2), with Membrane Microdomains and Their Relationship to Cell Localization and Activity

GPCRs receive signals from diverse messengers and activate G proteins that regulate downstream signaling effectors. Efficient signaling is achieved through the organization of these proteins in membranes. Thus, protein–lipid interactions play a critical role in bringing G proteins together in specif...

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Detalles Bibliográficos
Autores principales: Álvarez, Rafael, Escribá, Pablo V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953545/
https://www.ncbi.nlm.nih.gov/pubmed/36831093
http://dx.doi.org/10.3390/biomedicines11020557