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Secreted Frizzled Related Protein 5 (SFRP5) Serum Levels Are Decreased in Critical Illness and Sepsis and Are Associated with Short-Term Mortality

Sepsis is a major health burden with insufficiently understood mechanisms of inflammation and immune paralysis, leading to a life-threatening critical illness. The secreted frizzled related protein 5 (SFRP5) acts as an anti-inflammatory adipokine by antagonizing the Wnt5a pathway. The aim of this st...

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Detalles Bibliográficos
Autores principales: Hohlstein, Philipp, Brozat, Jonathan F., Schuler, Julia, Abu Jhaisha, Samira, Pollmanns, Maike R., Bündgens, Lukas, Wirtz, Theresa H., Yagmur, Eray, Hamesch, Karim, Weiskirchen, Ralf, Tacke, Frank, Trautwein, Christian, Koch, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953555/
https://www.ncbi.nlm.nih.gov/pubmed/36830849
http://dx.doi.org/10.3390/biomedicines11020313