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Identification of Novel Coloboma Candidate Genes through Conserved Gene Expression Analyses across Four Vertebrate Species

Ocular coloboma (OC) is a failure of complete optic fissure closure during embryonic development and presents as a tissue defect along the proximal–distal axis of the ventral eye. It is classed as part of the clinical spectrum of structural eye malformations with microphthalmia and anophthalmia, col...

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Detalles Bibliográficos
Autores principales: Trejo-Reveles, Violeta, Owen, Nicholas, Ching Chan, Brian Ho, Toms, Maria, Schoenebeck, Jeffrey J., Moosajee, Mariya, Rainger, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953556/
https://www.ncbi.nlm.nih.gov/pubmed/36830662
http://dx.doi.org/10.3390/biom13020293