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CXCR2 Antagonist RIST4721 Acts as a Potent Chemotaxis Inhibitor of Mature Neutrophils Derived from Ex Vivo-Cultured Mouse Bone Marrow

Neutrophils act as critical mediators of innate immunity, which depends on their rapid responses to chemokines followed by their migration towards sites of infection during chemotaxis. Chemokine receptors expressed on the surface of neutrophils mediate chemotaxis by activating contractile machinery...

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Detalles Bibliográficos
Autores principales: Szymczak, Klaudia, Pelletier, Margery G. H., Mackay, James M., Reid, DeAnne, Gaines, Peter C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953560/
https://www.ncbi.nlm.nih.gov/pubmed/36831016
http://dx.doi.org/10.3390/biomedicines11020479