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Micro Ribonucleic Acid−29a (miR−29a) Antagonist Normalizes Bone Metabolism in Osteogenesis Imperfecta (OI) Mice Model

Osteogenesis imperfecta (OI) is not curative nowadays. This study tried to unriddle the therapeutic potential of micro ribonucleic acid-29a (miR-29a) antagonist in treating OI in a mouse animal model (B6C3Fe a/a-Col1a2oim/J). We showed that the expression levels of miR-29a were higher in bone tissue...

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Detalles Bibliográficos
Autores principales: Ko, Jih-Yang, Wang, Feng-Sheng, Chen, Sung-Hsiung, Kuo, Shu-Jui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953572/
https://www.ncbi.nlm.nih.gov/pubmed/36831000
http://dx.doi.org/10.3390/biomedicines11020465