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Non-Healing Perianal Fistulas: A Clinical Model of Tissue Senescence Impairing Both Tissue Fibrosis and Regenerative Potential

Senescent cells and fibrosis are important components that impact the regenerative capacity of skin, particularly when considering chronic non-healing wounds. Anoderm and perianal fistulas in the setting of Crohn’s disease are clinically pathophysiological extremes with consequently different healin...

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Detalles Bibliográficos
Autores principales: Llaneras, Jason, Belza, Caitlyn C., Eisenstein, Samuel, Dobke, Marek K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953590/
https://www.ncbi.nlm.nih.gov/pubmed/36831073
http://dx.doi.org/10.3390/biomedicines11020537