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Low p16 Cytoplasmic Staining Predicts Poor Treatment Outcome in Patients with p16-Negative Locally Advanced Head and Neck Squamous Cell Carcinoma Receiving TPF Induction Chemotherapy

Human papillomavirus (HPV) has been proven to be associated with head and neck squamous cell carcinoma (HNSCC), and diffuse p16 unclear staining is usually considered as HPV-positive. The aim of the current study was to investigate the role of p16 cytoplasmic staining in HNSCC prognosis. A total of...

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Detalles Bibliográficos
Autores principales: Chen, Yen-Hao, Chien, Chih-Yen, Huang, Tai-Ling, Chiu, Tai-Jen, Wang, Yu-Ming, Fang, Fu-Min, Li, Shau-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953595/
https://www.ncbi.nlm.nih.gov/pubmed/36830875
http://dx.doi.org/10.3390/biomedicines11020339