Oligodendrocytes Prune Axons Containing α-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy?

α-Synucleinopathies are spreading neurodegenerative disorders characterized by the intracellular accumulation of insoluble aggregates populated by α-Synuclein (α-Syn) fibrils. In Parkinson’s disease (PD) and dementia with Lewy bodies, intraneuronal α-Syn aggregates are referred to as Lewy bodies in...

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Detalles Bibliográficos
Autores principales: De Nuccio, Francesco, Kashyrina, Marianna, Serinelli, Francesca, Laferrière, Florent, Lofrumento, Dario Domenico, De Giorgi, Francesca, Ichas, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953613/
https://www.ncbi.nlm.nih.gov/pubmed/36830639
http://dx.doi.org/10.3390/biom13020269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953613/
https://www.ncbi.nlm.nih.gov/pubmed/36830639
http://dx.doi.org/10.3390/biom13020269

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