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Oligodendrocytes Prune Axons Containing α-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy?
α-Synucleinopathies are spreading neurodegenerative disorders characterized by the intracellular accumulation of insoluble aggregates populated by α-Synuclein (α-Syn) fibrils. In Parkinson’s disease (PD) and dementia with Lewy bodies, intraneuronal α-Syn aggregates are referred to as Lewy bodies in...
Autores principales: | De Nuccio, Francesco, Kashyrina, Marianna, Serinelli, Francesca, Laferrière, Florent, Lofrumento, Dario Domenico, De Giorgi, Francesca, Ichas, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953613/ https://www.ncbi.nlm.nih.gov/pubmed/36830639 http://dx.doi.org/10.3390/biom13020269 |
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