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Smooth Muscle Cells of Dystrophic (mdx) Mice Are More Susceptible to Hypoxia; The Protective Effect of Reducing Ca(2+) Influx

Duchenne muscular dystrophy (DMD) is an inherited muscular disorder caused by mutations in the dystrophin gene. DMD patients have hypoxemic events due to sleep-disordered breathing. We reported an anomalous regulation of resting intracellular Ca(2+) ([Ca(2+)](i)) in vascular smooth muscle cells (VSM...

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Detalles Bibliográficos
Autores principales: Uryash, Arkady, Mijares, Alfredo, Estève, Eric, Adams, Jose A., Lopez, Jose R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953629/
https://www.ncbi.nlm.nih.gov/pubmed/36831159
http://dx.doi.org/10.3390/biomedicines11020623