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Gene Set Enrichment Analysis and Genetic Experiment Reveal Changes in Cell Signaling Pathways Induced by α-Synuclein Overexpression

Abnormal accumulation of alpha synuclein (α-Syn) in sporadic and familial Parkinson’s disease (PD) may be a key step in its pathogenesis. In this study, the expression matrix of the GSE95427 dataset after α-Syn overexpression in human glioma cell line H4 was obtained from the GEO database. We used t...

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Detalles Bibliográficos
Autores principales: Huang, Yusong, Wen, Dongjing, Yuan, Yao, Chen, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953658/
https://www.ncbi.nlm.nih.gov/pubmed/36830800
http://dx.doi.org/10.3390/biomedicines11020263