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Opposite Effects of mRNA-Based and Adenovirus-Vectored SARS-CoV-2 Vaccines on Regulatory T Cells: A Pilot Study

New-generation mRNA and adenovirus vectored vaccines against SARS-CoV-2 spike protein are endowed with immunogenic, inflammatory and immunomodulatory properties. Recently, BioNTech developed a noninflammatory tolerogenic mRNA vaccine (MOGm1Ψ) that induces in mice robust expansion of antigen-specific...

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Detalles Bibliográficos
Autores principales: La Gualana, Francesca, Maiorca, Francesca, Marrapodi, Ramona, Villani, Francesca, Miglionico, Marzia, Santini, Stefano Angelo, Pulcinelli, Fabio, Gragnani, Laura, Piconese, Silvia, Fiorilli, Massimo, Basili, Stefania, Casato, Milvia, Stefanini, Lucia, Visentini, Marcella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953737/
https://www.ncbi.nlm.nih.gov/pubmed/36831046
http://dx.doi.org/10.3390/biomedicines11020511