Temozolomide, Simvastatin and Acetylshikonin Combination Induces Mitochondrial-Dependent Apoptosis in GBM Cells, Which Is Regulated by Autophagy

SIMPLE SUMMARY: Glioblastoma multiforme (GBM) is a deadly brain tumor. The current chemotherapy strategies (including using temozolomide (TMZ)) is not very effective for GBM patients. Therefore, finding a new therapeutic strategy is demanding in the field of GBM. In our current investigations, we us...

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Detalles Bibliográficos
Autores principales: Hajiahmadi, Sima, Lorzadeh, Shahrokh, Iranpour, Rosa, Karima, Saeed, Rajabibazl, Masoumeh, Shahsavari, Zahra, Ghavami, Saeid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953749/
https://www.ncbi.nlm.nih.gov/pubmed/36829578
http://dx.doi.org/10.3390/biology12020302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953749/
https://www.ncbi.nlm.nih.gov/pubmed/36829578
http://dx.doi.org/10.3390/biology12020302

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