Oncolytic BHV-1 Is Sufficient to Induce Immunogenic Cell Death and Synergizes with Low-Dose Chemotherapy to Dampen Immunosuppressive T Regulatory Cells

SIMPLE SUMMARY: Immunotherapy is designed to stimulate the patient’s own immune system to fight their specific cancer. While immune checkpoint therapies work well for some tumors, they fail to work in tumors that are “immune cold”. Oncolytic viruses are viruses that preferentially target tumor cells...

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Detalles Bibliográficos
Autores principales: Davola, Maria Eugenia, Cormier, Olga, Vito, Alyssa, El-Sayes, Nader, Collins, Susan, Salem, Omar, Revill, Spencer, Ask, Kjetil, Wan, Yonghong, Mossman, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953776/
https://www.ncbi.nlm.nih.gov/pubmed/36831636
http://dx.doi.org/10.3390/cancers15041295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953776/
https://www.ncbi.nlm.nih.gov/pubmed/36831636
http://dx.doi.org/10.3390/cancers15041295

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