The Class IIA Histone Deacetylase (HDAC) Inhibitor TMP269 Downregulates Ribosomal Proteins and Has Anti-Proliferative and Pro-Apoptotic Effects on AML Cells

SIMPLE SUMMARY: Epigenetic alterations strongly contribute to the development of various types of cancer, including blood cancers such as acute myeloid leukemia (AML). Unlike genetic mutations, epigenetic changes in cancer are reversible. Therefore, targeted modification of epigenetic regulators, su...

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Detalles Bibliográficos
Autores principales: Urwanisch, Laura, Unger, Michael Stefan, Sieberer, Helene, Dang, Hieu-Hoa, Neuper, Theresa, Regl, Christof, Vetter, Julia, Schaller, Susanne, Winkler, Stephan M., Kerschbamer, Emanuela, Weichenberger, Christian X., Krenn, Peter W., Luciano, Michela, Pleyer, Lisa, Greil, Richard, Huber, Christian G., Aberger, Fritz, Horejs-Hoeck, Jutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953883/
https://www.ncbi.nlm.nih.gov/pubmed/36831382
http://dx.doi.org/10.3390/cancers15041039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953883/
https://www.ncbi.nlm.nih.gov/pubmed/36831382
http://dx.doi.org/10.3390/cancers15041039

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