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The KRAS-Mutant Consensus Molecular Subtype 3 Reveals an Immunosuppressive Tumor Microenvironment in Colorectal Cancer
SIMPLE SUMMARY: The poor prognosis outcome of patients with KRAS mutations (KRAS(mut)) was correlated with an immunosuppressive tumor microenvironment (TME). At the gene expression level and pathway analysis, KRAS(mut) tumor activates TGFβ signaling to reduced proinflammatory and cytokine gene signa...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953921/ https://www.ncbi.nlm.nih.gov/pubmed/36831441 http://dx.doi.org/10.3390/cancers15041098 |