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The KRAS-Mutant Consensus Molecular Subtype 3 Reveals an Immunosuppressive Tumor Microenvironment in Colorectal Cancer

SIMPLE SUMMARY: The poor prognosis outcome of patients with KRAS mutations (KRAS(mut)) was correlated with an immunosuppressive tumor microenvironment (TME). At the gene expression level and pathway analysis, KRAS(mut) tumor activates TGFβ signaling to reduced proinflammatory and cytokine gene signa...

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Detalles Bibliográficos
Autores principales:	Tanjak, Pariyada, Chaiboonchoe, Amphun, Suwatthanarak, Tharathorn, Acharayothin, Onchira, Thanormjit, Kullanist, Chanthercrob, Jantappapa, Suwatthanarak, Thanawat, Wannasuphaphol, Bundit, Chumchuen, Kemmapon, Suktitipat, Bhoom, Sampattavanich, Somponnat, Korphaisarn, Krittiya, Pongpaibul, Ananya, Poungvarin, Naravat, Grove, Harald, Riansuwan, Woramin, Trakarnsanga, Atthaphorn, Methasate, Asada, Pithukpakorn, Manop, Chinswangwatanakul, Vitoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953921/ https://www.ncbi.nlm.nih.gov/pubmed/36831441 http://dx.doi.org/10.3390/cancers15041098

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