Modeling Blast Crisis Using Mutagenized Chronic Myeloid Leukemia-Derived Induced Pluripotent Stem Cells (iPSCs)

Purpose: To model CML progression in vitro and generate a blast crisis (BC-CML) model in vitro in order to identify new targets. Methods: Three different CML-derived iPSC lines were mutagenized with the alkylating agent ENU on a daily basis for 60 days. Cells were analyzed at D12 of hematopoietic di...

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Detalles Bibliográficos
Autores principales: Imeri, Jusuf, Desterke, Christophe, Marcoux, Paul, Telliam, Gladys, Sanekli, Safa, Barreau, Sylvain, Erbilgin, Yucel, Latsis, Theodoros, Hugues, Patricia, Sorel, Nathalie, Cayssials, Emilie, Chomel, Jean-Claude, Bennaceur-Griscelli, Annelise, Turhan, Ali G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953961/
https://www.ncbi.nlm.nih.gov/pubmed/36831265
http://dx.doi.org/10.3390/cells12040598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953961/
https://www.ncbi.nlm.nih.gov/pubmed/36831265
http://dx.doi.org/10.3390/cells12040598

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