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Unique Metabolic Contexts Sensitize Cancer Cells and Discriminate between Glycolytic Tumor Types

SIMPLE SUMMARY: We sought to assess cancer cell viability in the context of glycolytic versus oxidative phosphorylation carbon source availability from cell lines and expression data from variably glycolytic human tumors. We performed an RNAi screen of genes consisting of the cytosolic machinery for...

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Detalles Bibliográficos
Autores principales: Chacon-Barahona, Jonathan A., MacKeigan, Jeffrey P., Lanning, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953999/
https://www.ncbi.nlm.nih.gov/pubmed/36831501
http://dx.doi.org/10.3390/cancers15041158