Methanodibenzo[b,f][1,5]dioxocins as Novel Glutaminase Inhibitor with Anti-Glioblastoma Potential

SIMPLE SUMMARY: The glutaminolysis pathway is recognized as one of the hallmarks of glioblastoma associated with tumor cell maintenance, survival, and aggressiveness. Targeting glutaminolysis emerged as a promising strategy for tumor treatments. Still, the development of glutaminase inhibitors is li...

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Detalles Bibliográficos
Autores principales: Murugesan, Akshaya, Kari, Sana, Shrestha, Anita, Assoah, Benedicta, Saravanan, Konda Mani, Murugesan, Monica, Thiyagarajan, Ramesh, Candeias, Nuno R., Kandhavelu, Meenakshisundaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954004/
https://www.ncbi.nlm.nih.gov/pubmed/36831355
http://dx.doi.org/10.3390/cancers15041010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954004/
https://www.ncbi.nlm.nih.gov/pubmed/36831355
http://dx.doi.org/10.3390/cancers15041010

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