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CAR-T Therapy in GBM: Current Challenges and Avenues for Improvement

SIMPLE SUMMARY: Clinical trials in glioblastoma (GBM) using CAR-T cells have not yielded tangible results. However, clinical and immunological observations from the trials have provided key insights into ways to limit toxicities and extend the antitumor efficacy of CAR-T cells. Incorporating recent...

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Detalles Bibliográficos
Autores principales: Pant, Ayush, Lim, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954019/
https://www.ncbi.nlm.nih.gov/pubmed/36831591
http://dx.doi.org/10.3390/cancers15041249