CTTN Overexpression Confers Cancer Stem Cell-like Properties and Trastuzumab Resistance via DKK-1/WNT Signaling in HER2 Positive Breast Cancer

SIMPLE SUMMARY: Cortactin (CTTN) is an actin-binding protein that is mainly known for its ability to promote cancer progression. It is unclear, however, whether CTTN affects tumor initiation and anti-tumor drug resistance in breast cancer. Here, we investigated the potential role of CTTN as a novel...

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Detalles Bibliográficos
Autores principales: Moon, So-Jeong, Choi, Hyung-Jun, Kye, Young-Hyeon, Jeong, Ga-Young, Kim, Hyung-Yong, Myung, Jae-Kyung, Kong, Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954024/
https://www.ncbi.nlm.nih.gov/pubmed/36831511
http://dx.doi.org/10.3390/cancers15041168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954024/
https://www.ncbi.nlm.nih.gov/pubmed/36831511
http://dx.doi.org/10.3390/cancers15041168

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