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CTTN Overexpression Confers Cancer Stem Cell-like Properties and Trastuzumab Resistance via DKK-1/WNT Signaling in HER2 Positive Breast Cancer
SIMPLE SUMMARY: Cortactin (CTTN) is an actin-binding protein that is mainly known for its ability to promote cancer progression. It is unclear, however, whether CTTN affects tumor initiation and anti-tumor drug resistance in breast cancer. Here, we investigated the potential role of CTTN as a novel...
Autores principales: | Moon, So-Jeong, Choi, Hyung-Jun, Kye, Young-Hyeon, Jeong, Ga-Young, Kim, Hyung-Yong, Myung, Jae-Kyung, Kong, Gu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954024/ https://www.ncbi.nlm.nih.gov/pubmed/36831511 http://dx.doi.org/10.3390/cancers15041168 |
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