NKG2A Immune Checkpoint in Vδ2 T Cells: Emerging Application in Cancer Immunotherapy

SIMPLE SUMMARY: Boosting effector T cell anti-tumor response remains a challenge, in part owing to the expression of immune checkpoints and their ligands, such as NKG2A and HLA-E. Targeting NKG2A by gene knockout or blocking antibodies improves the cytotoxicity of Vδ2 T cells, a specific subset of h...

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Detalles Bibliográficos
Autores principales: Cazzetta, Valentina, Depierreux, Delphine, Colucci, Francesco, Mikulak, Joanna, Mavilio, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954046/
https://www.ncbi.nlm.nih.gov/pubmed/36831606
http://dx.doi.org/10.3390/cancers15041264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954046/
https://www.ncbi.nlm.nih.gov/pubmed/36831606
http://dx.doi.org/10.3390/cancers15041264

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