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NKG2A Immune Checkpoint in Vδ2 T Cells: Emerging Application in Cancer Immunotherapy
SIMPLE SUMMARY: Boosting effector T cell anti-tumor response remains a challenge, in part owing to the expression of immune checkpoints and their ligands, such as NKG2A and HLA-E. Targeting NKG2A by gene knockout or blocking antibodies improves the cytotoxicity of Vδ2 T cells, a specific subset of h...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954046/ https://www.ncbi.nlm.nih.gov/pubmed/36831606 http://dx.doi.org/10.3390/cancers15041264 |