NEDD9 Overexpression Causes Hyperproliferation of Luminal Cells and Cooperates with HER2 Oncogene in Tumor Initiation: A Novel Prognostic Marker in Breast Cancer

SIMPLE SUMMARY: Neural precursor cell expressed, developmentally downregulated protein 9 (NEDD9) is an adaptor protein that promotes integrin/RTK signaling. The overexpression of NEDD9 in HER2+ breast cancer correlates with reduced relapse-free survival. We generated a conditional transgenic mouse m...

Descripción completa

Detalles Bibliográficos
Autores principales: Purazo, Marc L., Ice, Ryan J., Shimpi, Rahul, Hoenerhoff, Mark, Pugacheva, Elena N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954084/
https://www.ncbi.nlm.nih.gov/pubmed/36831460
http://dx.doi.org/10.3390/cancers15041119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954084/
https://www.ncbi.nlm.nih.gov/pubmed/36831460
http://dx.doi.org/10.3390/cancers15041119

Ejemplares similares