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Stereoselective Synthesis of Biologically Relevant Tetrahydropyridines and Dihydro-2H-pyrans via Ring-Expansion of Monocyclopropanated Heterocycles

[Image: see text] A stereoselective, scalable, and metal-free ring-expansion of monocyclopropanated pyrroles and furans has been developed, leading to value-added highly functionalized tetrahydropyridine and dihydro-2H-pyran derivatives. Featuring a cyclopropylcarbinyl cation rearrangement as the ke...

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Detalles Bibliográficos
Autores principales: Eckl, Robert, Fischer, Sebastian, Sonnleitner, Carina M., Schmidhuber, Daniel, Rehbein, Julia, Reiser, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954292/
https://www.ncbi.nlm.nih.gov/pubmed/36855453
http://dx.doi.org/10.1021/acsorginorgau.1c00042