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Systems Biology Approaches for the Improvement of Oncolytic Virus-Based Immunotherapies

SIMPLE SUMMARY: This review provides a roadmap to develop safe and effective OV-based future therapeutics by using several novel synthetic and system biology strategies. Integration of system and synthetic biology can improve the genetic design of OVs backbone, maintaining enough virulence-associate...

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Detalles Bibliográficos
Autores principales: Tripodi, Lorella, Sasso, Emanuele, Feola, Sara, Coluccino, Ludovica, Vitale, Maria, Leoni, Guido, Szomolay, Barbara, Pastore, Lucio, Cerullo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954314/
https://www.ncbi.nlm.nih.gov/pubmed/36831638
http://dx.doi.org/10.3390/cancers15041297