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Systems Biology Approaches for the Improvement of Oncolytic Virus-Based Immunotherapies
SIMPLE SUMMARY: This review provides a roadmap to develop safe and effective OV-based future therapeutics by using several novel synthetic and system biology strategies. Integration of system and synthetic biology can improve the genetic design of OVs backbone, maintaining enough virulence-associate...
Autores principales: | Tripodi, Lorella, Sasso, Emanuele, Feola, Sara, Coluccino, Ludovica, Vitale, Maria, Leoni, Guido, Szomolay, Barbara, Pastore, Lucio, Cerullo, Vincenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954314/ https://www.ncbi.nlm.nih.gov/pubmed/36831638 http://dx.doi.org/10.3390/cancers15041297 |
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