One out of Four: Kinetic Resolution of Stereoisomeric Mixtures of Secondary Alcohols with a Quaternary Carbon Atom in the β-Position by Cu–H-Catalyzed Enantioselective Silylation

[Image: see text] An enantio- and diastereoselective Cu–H-catalyzed silylation of acyclic secondary alcohols with a vicinal quaternary stereocenter is reported. The reaction kinetically selects one out of four stereoisomers, affording the fastest-reacting stereoisomer as the silyl ether in enantio-...

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Detalles Bibliográficos
Autores principales: Papadopulu, Zaneta, Kazeroonian, Novid, Irran, Elisabeth, Oestreich, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954319/
https://www.ncbi.nlm.nih.gov/pubmed/36855454
http://dx.doi.org/10.1021/acsorginorgau.1c00050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954319/
https://www.ncbi.nlm.nih.gov/pubmed/36855454
http://dx.doi.org/10.1021/acsorginorgau.1c00050

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