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International Differences in the Frequency of Chronic Obstructive Pulmonary Disease Exacerbations Reported in Three Clinical Trials

RATIONALE: Exacerbations of chronic obstructive pulmonary disease (COPD) are an important endpoint in multinational clinical treatment trials, but the observed event rate is often lower than anticipated and appears to vary between countries. OBJECTIVES: We investigated whether systematic differences...

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Detalles Bibliográficos
Autores principales: Calverley, Peter M. A., Martinez, Fernando J., Vestbo, Jørgen, Jenkins, Christine R., Wise, Robert, Lipson, David A., Cowans, Nicholas J., Yates, Julie, Crim, Courtney, Celli, Bartolome R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954323/
https://www.ncbi.nlm.nih.gov/pubmed/35363593
http://dx.doi.org/10.1164/rccm.202111-2630OC