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International Differences in the Frequency of Chronic Obstructive Pulmonary Disease Exacerbations Reported in Three Clinical Trials
RATIONALE: Exacerbations of chronic obstructive pulmonary disease (COPD) are an important endpoint in multinational clinical treatment trials, but the observed event rate is often lower than anticipated and appears to vary between countries. OBJECTIVES: We investigated whether systematic differences...
Autores principales: | Calverley, Peter M. A., Martinez, Fernando J., Vestbo, Jørgen, Jenkins, Christine R., Wise, Robert, Lipson, David A., Cowans, Nicholas J., Yates, Julie, Crim, Courtney, Celli, Bartolome R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Thoracic Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954323/ https://www.ncbi.nlm.nih.gov/pubmed/35363593 http://dx.doi.org/10.1164/rccm.202111-2630OC |
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