Targeting the ‘Undruggable’ Driver Protein, KRAS, in Epithelial Cancers: Current Perspective

This review summarizes recent development in synthetic drugs and biologics targeting intracellular driver genes in epithelial cancers, focusing on KRAS, and provides a current perspective and potential leads for the field. Compared to biologics, small molecule inhibitors (SMIs) readily penetrate cel...

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Detalles Bibliográficos
Autores principales: Lam, Kuen Kuen, Wong, Siew Heng, Cheah, Peh Yean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954350/
https://www.ncbi.nlm.nih.gov/pubmed/36831298
http://dx.doi.org/10.3390/cells12040631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954350/
https://www.ncbi.nlm.nih.gov/pubmed/36831298
http://dx.doi.org/10.3390/cells12040631

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