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Molecular Heterogeneity in BRAF-Mutant Gliomas: Diagnostic, Prognostic, and Therapeutic Implications

SIMPLE SUMMARY: Drugs targeting activating BRAF mutations have transformed the prognosis and treatment of MAPK-pathway-induced cancers. In neuro-oncology, the better knowledge of the MAPK pathway’s involvement in gliomagenesis offers hope in a subset of brain cancers where conventional therapies hav...

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Detalles Bibliográficos
Autores principales: Lhermitte, Benoit, Wolf, Thibaut, Chenard, Marie Pierre, Coca, Andres, Todeschi, Julien, Proust, François, Hirsch, Edouard, Schott, Roland, Noel, Georges, Guerin, Eric, Reita, Damien, Chammas, Agathe, Salmon, Alexandra, Martin, Sophie, Dontenwill, Monique, Entz-Werlé, Natacha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954401/
https://www.ncbi.nlm.nih.gov/pubmed/36831610
http://dx.doi.org/10.3390/cancers15041268