GEF-H1 Transduces FcεRI Signaling in Mast Cells to Activate RhoA and Focal Adhesion Formation during Exocytosis

When antigen-stimulated, mast cells release preformed inflammatory mediators stored in cytoplasmic granules. This occurs via a robust exocytosis mechanism termed degranulation. Our previous studies revealed that RhoA and Rac1 are activated during mast cell antigen stimulation and are required for me...

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Detalles Bibliográficos
Autores principales: Guo, Yitian, Negre, Judeah, Eitzen, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954420/
https://www.ncbi.nlm.nih.gov/pubmed/36831204
http://dx.doi.org/10.3390/cells12040537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954420/
https://www.ncbi.nlm.nih.gov/pubmed/36831204
http://dx.doi.org/10.3390/cells12040537

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