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GEF-H1 Transduces FcεRI Signaling in Mast Cells to Activate RhoA and Focal Adhesion Formation during Exocytosis

When antigen-stimulated, mast cells release preformed inflammatory mediators stored in cytoplasmic granules. This occurs via a robust exocytosis mechanism termed degranulation. Our previous studies revealed that RhoA and Rac1 are activated during mast cell antigen stimulation and are required for me...

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Detalles Bibliográficos
Autores principales:	Guo, Yitian, Negre, Judeah, Eitzen, Gary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954420/ https://www.ncbi.nlm.nih.gov/pubmed/36831204 http://dx.doi.org/10.3390/cells12040537

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