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Direct Cell Reprogramming and Phenotypic Conversion: An Analysis of Experimental Attempts to Transform Astrocytes into Neurons in Adult Animals

Central nervous system (CNS) repair after injury or disease remains an unresolved problem in neurobiology research and an unmet medical need. Directly reprogramming or converting astrocytes to neurons (AtN) in adult animals has been investigated as a potential strategy to facilitate brain and spinal...

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Detalles Bibliográficos
Autores principales: Dennison, Rachel, Usuga, Esteban, Chen, Harriet, Paul, Jacob Z., Arbelaez, Christian A., Teng, Yang D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954435/
https://www.ncbi.nlm.nih.gov/pubmed/36831283
http://dx.doi.org/10.3390/cells12040618