In Situ Imaging of O-Linked β-N-Acetylglucosamine Using On-Tissue Hydrolysis and MALDI Mass Spectrometry

SIMPLE SUMMARY: Post-translational O-glycosylation of proteins with N-acetylglucosamine serves as a cellular regulator that has been linked to cancer. This sugar’s variability is emerging as a metabolic biomarker in cancer, and here we investigate the use of mass spectrometry imaging to visualize th...

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Detalles Bibliográficos
Autores principales: Escobar, Edwin E., Seeley, Erin H., Serrano-Negrón, Jesús E., Vocadlo, David J., Brodbelt, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954453/
https://www.ncbi.nlm.nih.gov/pubmed/36831567
http://dx.doi.org/10.3390/cancers15041224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954453/
https://www.ncbi.nlm.nih.gov/pubmed/36831567
http://dx.doi.org/10.3390/cancers15041224

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